Description
This peptide (MRFFV) confers resistance to ketolide antibiotics, preventing antibiotic binding of bacterial ribosomes and allowing the continuation of protein synthesis.
This peptide (MRFFV) confers resistance to ketolide antibiotics, preventing antibiotic binding of bacterial ribosomes and allowing the continuation of protein synthesis.
Purity | ≥98% |
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Formula | C34H50N8O6S |
Formula Wt. | 698.9 |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet | K1674 Info Sheet PDF |
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Verdier L, Gharbi-Benarous J, Bertho G, et al. Antibiotic resistance peptides: interaction of peptides conferring macrolide and ketolide resistance with Staphylococcus aureus ribosomes: conformation of bound peptides as determined by transferred NOE experiments. Biochemistry. 2002 Apr 2;41(13):4218-29. PMID: 11914067.
Tripathi S, Kloss PS, Mankin AS. Ketolide resistance conferred by short peptides. J Biol Chem. 1998 Aug 7;273(32):20073-7. PMID: 9685347.