Description
Levamisoleisanimidazothiazolethatexhibitsimmunomodulatory,anti-parasitic,anti-helminthic,anti-angiogenic,andanticancerchemotherapeuticactivities.LevamisoleinhibitsalkalinephosphataseandmayactasanagoNISTatnicotinicacetylcholinereceptors(nAChRs).Inmultiplemyelomacells,levamisoleinducesDNAfragmentation,cytochromecreleaseandcaspase3activation,inhibitingcellularproliferation.Inothermodels,levamisolealsoinhibitsproliferationanddifferentiationofendothelialcellsandsuppressesgrowthofvarioustumorsinvivo.
References
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