Miconazoleisanimidazoleantifungalcompoundthatinhibitsergosterolsynthesisandfungalcellwallformation.MiconazoleisclinicallyusedtotreatfungalinfectionsandisespeciallyactiveagainstCandida.Miconazolealsoexhibitsanti-angiogenicactivities,decreasingexpressionofHIF-1αandVEGFinbreastcancerandgliomacells.Additionally,thiscompoundmayinhibitglucocorticoidreceptors.
| CasNo. | 22916-47-8 |
|---|---|
| Purity | ≥98% |
| Formula | C18H14Cl4N2O |
| FormulaWt. | 416.14 |
| ChemicalName | 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)-methoxy]ethyl]-1H-imidazole |
| IUPACName | 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole |
| Synonym | MoNISTatIV |
| MeltingPoint | 84.3°C |
| Solubility | Practicallyinsolubleinwater.Solubleinethanol(105mg/mL),methanol(66mg/mL) |
| Appearance | Whitetoyellowishpowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | M3309MSDSPDF |
|---|---|
| InfoSheet | M3309InfoSheetPDF |
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