Description
MoniliforminisamycotoxininitiallyproducedbyspeciesofFusariumthatcanbefoundingrainandvegetableproducts.Moniliforminmaydamagemyocardialtissueasaresultofdecreasingglutathioneperoxidaseandreductaseactivities,preventingglutathionerADIcalscavenging.Moniliforminalsodecreasescollagensynthesisandupregulatesexpressionofmatrixmetalloproteinases1and13(MMP1/13),inhibitingchondrocyteviABIlityinvitro.Inmacrophagesanddendriticcells,moniliforminaltersCDsurfaceMarkerexpressionanddecreasesendocytosisability.Moniliforminmayalsoinhibitpyruvatedehydrogenase.
References
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