L-TheanineisanaminoacidthatcanbefoundinCamelliaandBoletus;itisaglutamicacidanalog.L-theanineexhibitsneuroprotective,cognitionenhancing,anxiolytic,andantipsychoticactivities.L-TheanineisaweakagoNISTatAMPAandNMDAreceptors,increasingbrainDA,5-HT,andGABAlevels.Thiscompoundimprovesmemory,cognition,mood,andattentioninclinicalsettings.Inanimalmodelsofcerebralischemia,L-theanineinhibitsapoptosisofhippocampalneurons,improvingspatialmemory.
| CasNo. | 3081-61-6 |
|---|---|
| Purity | ≥98% |
| Formula | C7H14N2O3 |
| FormulaWt. | 174.19 |
| ChemicalName | N-Ethyl-L-glutamine |
| IUPACName | (2S)-2-amino-5-(ethylamino)-5-oxopentanoicacid |
| Synonym | Theanine |
| MeltingPoint | 210-215°C(dec) |
| Solubility | Solubleinwaterorethanol. |
| Appearance | WhiteCrystallinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | T2816MSDSPDF |
|---|---|
| InfoSheet | T2816InfoSheetPDF |
ParkSK,JungIC,LeeWK,etal.Acombinationofgreenteaextractandl-theanineimprovesmemoryandattentioninsubjectswithmildcognitiveimpairment:adouble-blindplacebo-controlledstudy.JMedFood.2011Apr;14(4):334-43.PMID:21303262.
RitsnerMS,MiodownikC,RatnerY,etal.L-theaninerelievespositive,activation,andanxietysymptomsinpatientswithschizophreniaandschizoaffectivedisorder:an8-week,randomized,double-blind,placebo-controlled,2-centerstudy.JClinPsychiatry.2011Jan;72(1):34-42.PMID:21208586.
HaskellCF,KennedyDO,MilneAL,etal.TheeffectsofL-theanine,caffeineandtheircombinationoncognitionandmood.BiolPsychol.2008Feb;77(2):113-22.PMID:18006208.
EgashiraN,IshigamiN,PuF,etal.Theaninepreventsmemoryimpairmentinducedbyrepeatedcerebralischemiainrats.PhytotherRes.2008Jan;22(1):65-8.PMID:17705146.
NathanPJ,LuK,GrayM,etal.TheneuropharmacologyofL-theanine(N-ethyl-L-glutamine):apossIBLeneuroprotectiveandcognitiveenhancingagent.JHerbPharmacother.2006;6(2):21-30.PMID:17182482.
