Description
Microginins are peptide protein phosphatase inhibitors initially produced by species of cyanobacteria Microcystis. Microginins inhibit zinc metalloproteinases such as leucine aminopeptidase and angiotensin-converting enzyme (ACE).
Microginins are peptide protein phosphatase inhibitors initially produced by species of cyanobacteria Microcystis. Microginins inhibit zinc metalloproteinases such as leucine aminopeptidase and angiotensin-converting enzyme (ACE).
Purity | ≥95% |
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Formula | C25H41N3O6S |
Formula Wt. | 511.67 |
Store Temp | -20°C |
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Ship Temp | Blue Ice |
Info Sheet | M3206 Info Sheet PDF |
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Schatz D, Keren Y, Vardi A, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environ Microbiol. 2007 Apr;9(4):965-70. PMID: 17359268.
Kraft M, Schleberger C, Weckesser J, et al. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 2006 Dec 22;580(30):6943-7. PMID: 17157838.
Runnage ME, Burke AJ, Davies SG, et al. Asymmetric Synthesis of the N-terminal component of Microginin: (2S,3R)-3-Amino-2-Hydroxydecanoic Acid, its (2R,3R)-Epimer and (3R)-3-Aminodecanoic Acid. Tetrahedron: Asymmetry. 1995;6(1):165-176.