Fenbufenisanon-steroidalanti-inflammatorydrug(NSAID)thatinhibitsCOX-1andCOX-2;itexhibitsanti-inflammatory,analgesic,andantioxidativeactivities.Fenbufenisclinicallyusedtotreatrheumatoidarthritis,tendinitis,andankylosingspondylitis.Invitro,fenbufenscavengesO2rADIcalsandROS.
| CasNo. | 36330-85-5 |
|---|---|
| Purity | ≥98% |
| Formula | C16H14O3 |
| FormulaWt. | 254.28 |
| ChemicalName | γ-Oxo-[1,1"-biphenyl]-4-butanoicacid |
| IUPACName | 4-oxo-4-(4-phenylphenyl)butanoicacid |
| Synonym | Bufemid;Cinopol;Lederfen |
| MeltingPoint | 185-187°C |
| Solubility | Solubleindimethylsulfoxide. |
| Appearance | WhiteorAlmostWhiteCrystallinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | F1652MSDSPDF |
|---|---|
| InfoSheet | F1652InfoSheetPDF |
MooreRA,DerryS,McQuayHJ.Singledoseoralfenbufenforacutepostoperativepaininadults.CochraneDatabaseSystRev.2009Oct7;(4):CD007547.PMID:19821427.
CostaD,MoutinhoL,LimaJL,etal.Antioxidantactivityandinhibitionofhumanneutrophiloxidativeburstmediatedbyarylpropionicacidnon-steroidalanti-inflammatorydrugs.BiolPharmBull.2006Aug;29(8):1659-70.PMID:16880623.
