Gabapentinexhibitsantiepileptic/anticonvulsant,sedative,analgesic,andantinociceptiveactivities.GabapentinisaGABAanalogthatdoesnotbindGABAreceptors.Gabapentinbindstheα2δsubunitofvoltage-gatedCa2+channels,decreasingCa2+currentsandinhibitingCa2+signaling;gabapentinalsoactivatesadenosineA1receptors,bindsNMDAreceptors,andpotentiatestheeffectsofGABAsignaling.Gabapentinisclinicallyusedtopreventseizuresandtotreatneuropathic,inflammatory,andcancer-relatedpain.
| CasNo. | 60142-96-3 |
|---|---|
| Purity | ≥98% |
| Formula | C9H17NO2 |
| FormulaWt. | 171.24 |
| ChemicalName | 1-(Aminomethyl)-cyclohexaneaceticacid |
| IUPACName | 2-[1-(aminomethyl)cyclohexyl]aceticacid |
| Synonym | GOE-3450;Neurontin |
| MeltingPoint | 162-166°C |
| Solubility | Solubleinwater(pH7.4). |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | G0106MSDSPDF |
|---|---|
| InfoSheet | G0106InfoSheetPDF |
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