Parecoxibisaprodrugofvaldecoxibandnon-steroidalanti-inflammatorydrug(NSAID)thatexhibitsanti-inflammatoryandanalgesicactivities.ParecoxibinhibitsCOX-2andpreventsneuropathicpain-inducedhypersensitivityinanimalmodelsofchronicconstrictiveinjury.
| CasNo. | 198470-85-8 |
|---|---|
| Purity | ≥99% |
| Formula | C19H18N2O4SNa |
| FormulaWt. | 392.40 |
| IUPACName | sodium;[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonyl-propanoylazanide |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | P0369InfoSheetPDF |
|---|
ZhouGB,LiHY,JiJQ,etal.AnalgesiceffectofCOXinhibitorsanditsmechanisminaratmodelofneuropathicpain.NanFangYiKeDaXueXueBao.2011Oct;31(10):1764-6.PMID:22027786.
KoppertW,WehrfritzA,KörberN,etal.Thecyclooxygenaseisozymeinhibitorsparecoxibandparacetamolreducecentralhyperalgesiainhumans.Pain.2004Mar;108(1-2):148-53.PMID:15109518.
