Nefazodoneisanatypicalantidepressantthatinhibits5-HT2receptors,SEROtonintransporters(SERT),norepinephrinetransporters(NET),andhumanether-a-go-go-related(hERG)K+channels.Nefazodonedecreasesimmobilitytimeintheforcedswimtestandisclinicallyusedtotreatdepression,panicdisorder,andpost-traumaticstressdisorder(PTSD).
| CasNo. | 82752-99-6 |
|---|---|
| Purity | ≥98% |
| Formula | C25H32ClN5O2•HCl |
| FormulaWt. | 506.48 |
| ChemicalName | 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-onehydrochloride |
| IUPACName | 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one;hydrochloride |
| Synonym | BMY-13754;MJ-13754-1;Dutonin;Serzone |
| MeltingPoint | 186-187°C |
| Solubility | Slightlysolubleinwater. |
| Appearance | AWhitetooff-WhiteCrystallinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | N1822MSDSPDF |
|---|---|
| InfoSheet | N1822InfoSheetPDF |
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