LKT/神经激肽B/N1978/5毫克-免疫在线蚂蚁淘旗下平台

商品详细LKT/神经激肽B/N1978/5毫克

LKT/神经激肽B/N1978/5毫克

商品编号： N1978-5mg

品牌： lktlabs

市场价： ¥4520.00

美元价： 2712.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDN1978

CasNo.86933-75-7

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

NeurokininBisanendogenousneuromodulatorypeptidethatbindstheneurokinin3(NK3)receptorandisco-expressedwithkisspeptinanddynorphinA.NeurokininBincreasesosteoclastactivityandboneresorptioninvitroandinducescontractioninilealsmoothmusclecells.NeurokininBalsoexhibitsneuroprotectiveactivity,decreasingtoxiceffectsofamyloid-β(Aβ)byincreasingsuperoxidedismutase(SOD)activity,decreasingmonoamineoxidase(MAO)activity,andrestoringintracellularCa2+levels.NeurokininBmayalsobeusedasabioMarkerforpregnancy-inducedhypertensionandpre-eclampsia.

ProductInfo

CasNo.	86933-75-7
Purity	≥95%
Formula	C₅₅H₇₉N₁₃O₁₄S₂
FormulaWt.	1210.45
IUPACName	3-amino-4-[[1-[[1-[[1-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoicacid
Synonym	NeurokininK
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

InfoSheet	N1978InfoSheetPDF

References

IchikiT,KuroishiKN,GunjigakeKK,etal.NeurokininBactivatestheformationandboneresorptionactivityofratosteoclasts.Neuropeptides.2011Jun;45(3):239-44.PMID:21514667

ManthaAK,MoorthyK,CowsikSM,etal.NeuroprotectiveroleofneurokininB(NKB)onbeta-amyloid(25-35)inducedtoxicityinagingratbrainsynaptosomes:involvementinoxidativestressandexcitotoxicity.Biogerontology.2006Feb;7(1):1-17.PMID:16518716.

PageNM,WoodsRJ,GardinerSM,etal.ExcessiveplacentalsecretionofneurokininBduringthethirdtrimestercausespre-eclampsia.Nature.2000Jun15;405(6788):797-800.PMID:10866201.

SuzukiN,MizunoK,GomiY.Tachykinin-inducedcontractionsinthecircularmuscleofguineapigileum.JpnJPharmacol.1994Jul;65(3):233-40.PMID:7528285.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂