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商品详细LKT/NEUROPEPTIDE FF/N1984/10 mg
LKT/NEUROPEPTIDE FF/N1984/10 mg
LKT/NEUROPEPTIDE FF/N1984/10 mg
商品编号: N1984-10mg
品牌: lktlabs
市场价: ¥8060.00
美元价: 4836.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Neuropeptide FF is an endogenous RF amide family peptide that exhibits anti-inflammatory and anti-analgesic activities. Neuropeptide FF binds NPFF1/2 receptors in the brain, regulating blood pressure and hormone secretion. In LPS-stimulated macrophages, neuropeptide FF decreases NO production and inhibits NF-κB translocation; in animal models, it suppresses carrageenan-induced edema. Additionally, neuropeptide FF inhibits opioid-induced stress-mediated analgesia in the forced swim test, displaying anti-opioid activity.

Product Info

Cas No.

99566-27-5

Purity

≥95%

Formula

C54H76N14O10

Formula Wt.

1081.3

IUPAC Name

(2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[(2-amino-3-phenylpropanoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide

Synonym

NPFF; Octapeptide F8FA; F-8-F-NH2, Neuro FF Morphine Modulating Neuro F-8-F-NH2.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

N1984 Info Sheet PDF

References

Sun YL, Zhang XY, Sun T, et al. The anti-inflammatory potential of neuropeptide FF in vitro and in vivo. Peptides. 2013 Sep;47:124-32. PMID: 23856454.

Jhamandas JH, Goncharuk V. Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol (Lausanne). 2013 Feb 7;4:8. PMID: 23404625.

Li N, Han ZL, Fang Q, et al. Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice. Behav Brain Res. 2012 Aug 1;233(2):428-33. PMID: 22659392.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂