LKT/醋酸戈舍林/G5772/1mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/醋酸戈舍林/G5772/1mg

LKT/醋酸戈舍林/G5772/1mg

商品编号： G5772-1mg

品牌： lktlabs

市场价： ¥4720.00

美元价： 2832.00

产地：美国(厂家直采)

公司：

产品分类：多肽

公司分类： peptides

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDG5772

CasNo.145781-92-6

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

GoserelinactsasapeptideagoNISTatthegonadotropin-releasinghormone(GnRH)orluteinizinghormonereleasinghormone(LHRH)receptor,stimulatingreleaseoffollicle-stimulatinghormone(FSH)andluteinizinghormone(LH)anddecreasingandrogenlevels.Goserelinexhibitsanticancerchemotherapeuticbenefit,inhibitingcellproliferationandtumorgrowthincellularandanimalmodelsofprostatecancer,likelythroughindirectactivationofPKCandinhibitionofEGFRactivity.GoserelinalsoinhibitscellproliferationandtumorgrowthincellularandanimalmodelsofovariancancerthroughamechanismthatinvolvesinhibitionofAktphosphorylation.Inotheranimalmodels,goserelinincreasesboneelongation.

ProductInfo

CasNo.	145781-92-6
Purity	≥95%
Formula	C₅₉H₈₄N₁₈O₁₄C₂H₄O₂
FormulaWt.	1329.48
IUPACName	aceticacid;N-[1-[[1-[[1-[[1-[[1-[[1-[[1-[2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

InfoSheet	G5772InfoSheetPDF
Brochures	PI3K-Akt-mTORCPathwayBooklet

References

DettiL,UhlmannRA,ZhangJ,etal.Goserelinfostersboneelongationbutdoesnotpreventovariandamageincyclophosphamide-treatedprepubertalmice.FertilSteril.2014Jan23.pii:S0015-0282(13)03460-2.[Epubaheadofprint].PMID:24462062.

ZhangY,DingJX,TaoX,etal.Goserelincaninhibitovariancancerproliferationandsimultaneouslyprotectovarianfunctionfromcisplatin:aninvitroandinvivostudy.JChemother.2013Apr;25(2):96-103.PMID:23684357.

WellsA,SoutoJC,SolavaJ,etal.Luteinizinghormone-releasinghormoneagonistlimitsDU-145prostatecancergrowthbyattenuatingepidermalgrowthfactorreceptorsignaling.ClinCancerRes.2002Apr;8(4):1251-7.PMID:11948140.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂