Growthhormonereleasingfactor(GHRForGHRH)isanendogenouspeptidehormonethatbindstheGHRHreceptorintheanteriorpituitary,inducingthereleaseofgrowthhormone.GHRFpromotesnon-REMslowwavesleepinanimalmodels.Additionally,GHRFdecreasesfatsynthesisinADIposetissueinvivo,andincreaseslocomotoractivityinotheranimalmodels.Ingranulosacells,GHRFstimulatesactivityofplasminogenactivator,playingaroleinfolliculardevelopment.
| CasNo. | 83930-13-6 |
|---|---|
| Purity | ≥95% |
| Formula | C215H358N72O66S |
| FormulaWt. | 5039.7 |
| Synonym | Somatorelin,Somatoliberin(humanpancreaticislet);GHRF;GHRH |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | G2870InfoSheetPDF |
|---|
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LiesmanJS,McNamaraJP,CapucoAV,etal.Comparisonofgrowthhormone-releasingfactorandsomatotropin:lipidandglucosemetabolismindairycows.JDairySci.1995Oct;78(10):2159-66.PMID:8598400.
KarakjiEG,TsangBK.Growthhormonereleasingfactorandvasoactiveintestinalpeptidestimulateratgranulosacellplasminogenactivatoractivityinvitroduringfolliculardevelopment.MolCellEndocrinol.1995Jan;107(1):105-12.PMID:7796929.
AlvarezXA,CacabelosR.Influenceofgrowthhormone(GH)andGH-releasingfactoronlocomotoractivityinrats.Peptides.1993Jul-Aug;14(4):707-12.PMID:8234013.
