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当前位置: 首页 > 产品中心 > peptides > LKT/层粘连蛋白肽CDPGYIGSR/L0251/1 mg
商品详细LKT/层粘连蛋白肽CDPGYIGSR/L0251/1 mg
LKT/层粘连蛋白肽CDPGYIGSR/L0251/1 mg
LKT/层粘连蛋白肽CDPGYIGSR/L0251/1 mg
商品编号: L0251-1mg
品牌: lktlabs
市场价: ¥3140.00
美元价: 1884.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽
公司分类: peptides
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

This nonapeptide is equivalent to a sequence found on the B1 chain of laminin (925-933); it exhibits vasoconstrictive, anti-metastatic, and anti-angiogenic activities. This peptide increases vascular tone, producing vasoconstriction and inducing Ca2+ influx in vascular smooth muscle cells; it also activates nonselective cation channels. In vitro, this peptide inhibits angiogenesis and cell migration. In vivo, this peptide inhibits growth of sarcoma 180 tumors and Lewis lung carcinoma tumors. Like other laminin peptides, this sequence can be used in combination with chemotherapeutics to deliver the drug to target tumor tissues.

Product Info

Cas No.

110590-60-8

Purity

≥98%

Formula

C40H62N12O14S

Formula Wt.

967.06

IUPAC Name

L-Cysteinyl-L-α-aspartyl-L-prolylglycyl-L-tyrosyl-L-isoleucylglycyl-L-seryl-N5-(diaminomethylene)-L-ornithine

Synonym

Laminin (925-933)

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

L0251 Info Sheet PDF

References

Wenzel D, Koch M, Matthey M, et al. Identification of a novel vasoconstrictor peptide specific for the systemic circulation. Hypertension. 2012 Jun;59(6):1256-62. PMID: 22547445.

Sakamoto N, Iwahana M, Tanaka NG, et al. Inhibition of angiogenesis and tumor growth by a synthetic laminin peptide, CDPGYIGSR-NH2. Cancer Res. 1991 Feb 1;51(3):903-6. PMID: 1703042.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂