Description
Myelin basic protein (68-82) is an immunodominant peptide epitope observed in multiple sclerosis; it may be used to induce immune tolerance and downregulate T cell reactivity to myelin.
Myelin basic protein (68-82) is an immunodominant peptide epitope observed in multiple sclerosis; it may be used to induce immune tolerance and downregulate T cell reactivity to myelin.
Purity | ≥95% |
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Formula | C71H113N23O28 |
Formula Wt. | 1736.8 |
Synonym | MBP |
Appearance | White to off white powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet | M9646 Info Sheet PDF |
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Mantzourani ED, Platts JA, Brancale A, et al. Molecular dynamics at the receptor level of immunodominant myelin basic protein epitope 87-99 implicated in multiple sclerosis and its antagonists altered peptide ligands: triggering of immune response. J Mol Graph Model. 2007 Sep;26(2):471-81. PMID: 17392002.
Liu JQ, Bai XF, Shi FD, et al. Inhibition of experimental autoimmune encephalomyelitis in Lewis rats by nasal administration of encephalitogenic MBP peptides: synergistic effects of MBP 68-86 and 87-99. Int Immunol. 1998 Aug;10(8):1139-48. PMID: 9723700.