Description
Myelinbasicprotein(87-99)isanimmunodominantpeptideepitopeobservedinmultiplesclerosis;itmaybeusedtoinduceimmunetoleranceanddownregulateTcellreactivitytomyelin.
Myelinbasicprotein(87-99)isanimmunodominantpeptideepitopeobservedinmultiplesclerosis;itmaybeusedtoinduceimmunetoleranceanddownregulateTcellreactivitytomyelin.
Purity | ≥95% |
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Formula | C74H114N20O17 |
FormulaWt. | 1555.8 |
Synonym | MBP |
Appearance | Whitetooffwhitepowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | M9644InfoSheetPDF |
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MantzouraniED,PlattsJA,BrancaleA,etal.Moleculardynamicsatthereceptorlevelofimmunodominantmyelinbasicproteinepitope87-99implicatedinmultiplesclerosisanditsantagoNISTsalteredpeptideligands:triggeringofimmuneresponse.JMolGraphModel.2007Sep;26(2):471-81.PMID:17392002.
LiuJQ,BaiXF,ShiFD,etal.InhibitionofexperimentalautoimmuneencephalomyelitisinLewisratsbynasaladministrationofencephalitogenicMBPpeptides:synergisticeffectsofMBP68-86and87-99.IntImmunol.1998Aug;10(8):1139-48.PMID:9723700.