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当前位置: 首页 > 产品中心 > clinical_research > LKT/CHLOROPHYLLIN SODIUM-COPPER SALT/C2945/5 g
商品详细LKT/CHLOROPHYLLIN SODIUM-COPPER SALT/C2945/5 g
LKT/CHLOROPHYLLIN SODIUM-COPPER SALT/C2945/5 g
LKT/CHLOROPHYLLIN SODIUM-COPPER SALT/C2945/5 g
商品编号: C2945-5g
品牌: lktlabs
市场价: ¥600.00
美元价: 360.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Chlorophyllinisasemi-syntheticderivativeofchlorophyllthatiscommerciallyusedasafoodadditiveandcoloringagent.Chlorophyllinexhibitsanti-angiogenic,anticancerchemotherapeutic,andchemopreventiveactivities.Chlorophyllincanactasaphotosensitizer,inducingapoptosisandautophagyunderUVlightinbladdercancercells.Invivo,chlorophyllindecreasesexpressionofHDACs,VEGF,VEGFR2,andHIF-1αandsuppressesWnt/β-cateninsignaling.Invitro,thiscompounddecreasesDNAadductformationinducedbybenzo[a]pyrene.Chlorophyllinalsodecreasescarcinogenesis,mortality,andtumornumberinanimalmodelsofDBP-inducedcarcinogenesis.

ProductInfo

CasNo.

11006-34-1

Purity

≥98%

Formula

C34H31CuN4Na3O6

FormulaWt.

724.15

IUPACName

magnesium;3-[20-(carboxylatomethyl)-18-(dioxidomethylidene)-8-ethenyl-13-ethyl-3,7,12,17-tetramethyl-2,3-dihydroporphyrin-23-id-2-yl]propanoate;hydron

Synonym

ChlorophyllinA

Solubility

Solubleinwater,slightlysolubleinalcoholandchloroform

Appearance

Darkgreenpowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

C2945MSDSPDF

InfoSheet

C2945InfoSheetPDF

Brochures

WNTBooklet

References

LihuanD,JingcunZ,NingJ,etal.Photodynamictherapywiththenovelphotosensitizerchlorophyllinfinducesapoptosisandautophagyinhumanbladdercancercells.LasersSurgMed.2014Apr;46(4):319-34.PMID:24464873.

NaginiS,VidyaPriyadarsiniR,VeeravarmalV,etal.ChlorophyllinabrogatescanonicalWnt/β-cateninsignalingandangiogenesistoinhibitthedevelopmentofDMBA-inducedhamstercheekpouchcarcinomas.CellOncol(Dordr).2012Oct;35(5):385-95.Erratumin:CellOncol(Dordr).2013Apr;36(2):179.PMID:22983718.

KeshavaC,DiviRL,EinemTL,etal.Chlorophyllinsignificantlyreducesbenzo[a]pyrene-DNAadductformationandalterscytochromeP4501A1and1B1expressionandERODactivityinnormalhumanmammaryepithelialcells.EnvironMolMutagen.2009Mar;50(2):134-44.PMID:19152381.

CastroDJ,LöhrCV,FischerKA,etal.Identifyingefficaciousapproachestochemopreventionwithchlorophyllin,purifiedchlorophyllsandfreeze-driedspinachinamousemodeloftransplacentalcarcinogenesis.Carcinogenesis.2009Feb;30(2):315-20.PMID:19073876.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂