Phenylethyl3-methylcaffeateexhibitsanticancerchemotherapeuticandchemopreventiveactivities.Phenylethyl-3-methylcaffeateisahydroxycinnamicacidandderivativeofmethylcaffeate.Thiscompounddecreasestheincidence,number,andvolumeoftumorsinvariousanimalmodels.Additionally,thiscompoundinducesapoptosisandinhibitscarcinogenesisinanimalmodelsofcoloncancer.
| CasNo. | 71835-85-3 |
|---|---|
| Purity | ≥97% |
| Formula | C18H18O4 |
| FormulaWt. | 298.33 |
| ChemicalName | 2-Phenylethyl3-(4-hydroxy-3-methoxyphenyl)-2-propenoate |
| IUPACName | 2-phenylethyl(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate |
| Synonym | CCRIS7791 |
| MeltingPoint | 80-81°C |
| Solubility | Solinethanol,methanol,andmostorganicsolvents. |
| Appearance | Off-whitesolid |
| StoreTemp | 4°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | P1917InfoSheetPDF |
|---|
SamahaHS,KelloffGJ,SteeleV,etal.Modulationofapoptosisbysulindac,curcumin,phenylethyl-3-methylcaffeate,and6-phenylhexylisothiocyanate:apoptoticindexasabioMarkerincoloncancerchemopreventionandpromotion.CancerRes.1997Apr1;57(7):1301-5.PMID:9102217.
RaoCV,DesaiD,RivensonA,etal.Chemopreventionofcoloncarcinogenesisbyphenylethyl-3-methylcaffeate.CancerRes.1995Jun1;55(11):2310-5.PMID:7757981.
