Description
PHT-427isaninhibitorofPDK1andAktthatexhibitsanticancerchemotherapeuticactivity,inhibitingtumorgrowthinanimalmodelsofbreastcancerandnon-smallcelllungcancer(NSCLC).
PHT-427isaninhibitorofPDK1andAktthatexhibitsanticancerchemotherapeuticactivity,inhibitingtumorgrowthinanimalmodelsofbreastcancerandnon-smallcelllungcancer(NSCLC).
CasNo. | 1191951-57-1 |
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Purity | ≥98% |
Formula | C20H31N3O2S2 |
FormulaWt. | 409.61 |
IUPACName | 4-dodecyl-N-(1,3,4-thiADIazol-2-yl)benzenesulfonamide |
Synonym | PHT427 |
Appearance | WhiteCrystalPowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | P3076InfoSheetPDF |
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Brochures | PI3K-Akt-mTORCPathwayBooklet |
MeuilletEJ,ZuoheS,LemosR,etal.MolecularpharmacologyandantitumoractivityofPHT-427,anovelAkt/phosphatidylinositide-dependentproteinkinase1pleckstrinhomologydomaininhibitor.MolCancerTher.2010Mar;9(3):706-17.PMID:20197390.