Description
PHT-427isaninhibitorofPDK1andAktthatexhibitsanticancerchemotherapeuticactivity,inhibitingtumorgrowthinanimalmodelsofbreastcancerandnon-smallcelllungcancer(NSCLC).
PHT-427isaninhibitorofPDK1andAktthatexhibitsanticancerchemotherapeuticactivity,inhibitingtumorgrowthinanimalmodelsofbreastcancerandnon-smallcelllungcancer(NSCLC).
| CasNo. | 1191951-57-1 |
|---|---|
| Purity | ≥98% |
| Formula | C20H31N3O2S2 |
| FormulaWt. | 409.61 |
| IUPACName | 4-dodecyl-N-(1,3,4-thiADIazol-2-yl)benzenesulfonamide |
| Synonym | PHT427 |
| Appearance | WhiteCrystalPowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | P3076InfoSheetPDF |
|---|---|
| Brochures | PI3K-Akt-mTORCPathwayBooklet |
MeuilletEJ,ZuoheS,LemosR,etal.MolecularpharmacologyandantitumoractivityofPHT-427,anovelAkt/phosphatidylinositide-dependentproteinkinase1pleckstrinhomologydomaininhibitor.MolCancerTher.2010Mar;9(3):706-17.PMID:20197390.