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商品详细LKT/ESTRADIOL/E7376/5 g
LKT/ESTRADIOL/E7376/5 g
LKT/ESTRADIOL/E7376/5 g
商品编号: E7376-5g
品牌: lktlabs
市场价: ¥4580.00
美元价: 2748.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

EstrADIolisanendogenousestrogenicsteroidhormonecommonlyusedinoralcontraceptivesandhormonereplacementtherapy(HRT).Estradiolregulatesestrousandmenstrualreproductivecycles,inducesgrowthinreproductiveorgans,andincreasessecretionofluteinizinghormone(LH).Estradiolinhibitsacetylcholine-inducedvascularconstrictioninpost-menopausalwomenandinhibitsspermapoptosisinvitro.Estradioldisplayssomeadditionalanticancerpotential,inhibitinggrowthandproliferationofprostatecancercells.Estradiolalsoexhibitsantioxidativebenefit,inhibitingoxidativestress-inducedcelldeathanddamageandinhibitingglutamate-inducedneurotoxicity.

ProductInfo

CasNo.

50-28-2

Purity

≥97%

Formula

C18H24O2

FormulaWt.

272.38

ChemicalName

(17β)-Estra-1,3,5(10)-triene-3,17-diol

IUPACName

(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol

Synonym

Dimenformon;Estrace;Estraderm;Evorel;Macrodiol;Menorest;ProfoliolB;Systen;Vagifem;Zumenon

MeltingPoint

173-179°C

Solubility

Solubleinalcohol(35mg/mL),acetone,dioxane,andotherorganicsolvent.Insolubleinwater.

Appearance

WhiteoralmostwhiteCrystalPowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

E7376MSDSPDF

InfoSheet

E7376InfoSheetPDF

References

PentikäinenV,ErkkiläK,SuomalainenL,etal.Estradiolactsasagermcellsurvivalfactorinthehumantestisinvitro.JClinEndocrinolMetab.2000May;85(5):2057-67.PMID:10843196.

BehlC,WidmannM,TrappT,etal.17-betaestradiolprotectsneuronsfromoxidativestress-inducedcelldeathinvitro.BiochemBiophysResCommun.1995Nov13;216(2):473-82.PMID:7488136.

CollinsP,RosanoGM,SarrelPM,etal.17beta-Estradiolattenuatesacetylcholine-inducedcoronaryarterialconstrictioninwomenbutnotmenwithcoronaryheartdisease.Circulation.1995Jul1;92(1):24-30.PMID:7788912.

CarrubaG,PfefferU,FecarottaE,etal.Estradiolinhibitsgrowthofhormone-nonresponsivePC3humanprostatecancercells.CancerRes.1994Mar1;54(5):1190-3.PMID:8118804.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂