Norethindroneisaprogestogensteroidhormonethatisclinicallyusedinoralcontraceptives.Norethindronedecreaseslevelsofluteinizinghormone(LH)andfollicle-stimulatinghormone(FSH).NorethindronealsodecreasesHDLandincreaseslipidperoxidationduetoitshighlipophilicity.
| CasNo. | 68-22-4 |
|---|---|
| Purity | ≥98% |
| Formula | C20H26O2 |
| FormulaWt. | 298.42 |
| ChemicalName | 17α-17-Hydroxy-19-norpregnen-4-20-yn-3-one |
| IUPACName | (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one |
| Synonym | Menzol;Micronovum;Norlutin;Utovaln |
| MeltingPoint | 203-204°C |
| Solubility | Insolubleinwater.Solubleinacetone,ethanol,chloroformanddioxane. |
| Appearance | Off-WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | N5767InfoSheetPDF |
|---|
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CouzinetB,YoungJ,BraillyS,etal.Theantigonadotropicactivityofprogestins(19-nortestosteroneand19-norprogesteronederivatives)isnotmediatedthroughtheandrogenreceptor.JClinEndocrinolMetab.1996Dec;81(12):4218-23.PMID:8954018.
