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当前位置: 首页 > 产品中心 > clinical_research > LKT/HALOPERIDOL/H0142/1 g
商品详细LKT/HALOPERIDOL/H0142/1 g
LKT/HALOPERIDOL/H0142/1 g
LKT/HALOPERIDOL/H0142/1 g
商品编号: H0142-1g
品牌: lktlabs
市场价: ¥880.00
美元价: 528.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Haloperidolisabutyrophenoneantipsychoticthatisclinicallyusedtotreatpsychosis,obsessive-compulsivedisorder,andvariousotherpersonalitydisorders.HaloperidolactsasanantagoNISTatD2receptors,α1-adrenergicreceptors,5-HT2Areceptors,andσ1receptors;italsoactivatesσ2receptors.

ProductInfo

CasNo.

52-86-8

Purity

≥95%

Formula

C21H23ClFNO2

FormulaWt.

375.86

ChemicalName

1-Butanone,4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-

IUPACName

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

Synonym

Haldol;Halosten;Linton;Keselan;Aloperidin;Brotopon;Dozic.

MeltingPoint

148-149.4°C

Solubility

Solubleinchloroform,ethanol(16mg/mL),methanol,acetoneorbenzene.Insolubleinwater.

Appearance

WhiteCrystalPowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

H0142MSDSPDF

InfoSheet

H0142InfoSheetPDF

References

CobosEJ,delPozoE,BaeyensJM.IrreversIBLeblockadeofsigma-1receptorsbyhaloperidolanditsmetabolitesinguineapigbrainandSH-SY5Yhumanneuroblastomacells.JNeuRochem.2007Aug;102(3):812-25.PMID:17419803.

ColabufoNA,BerardiF,ContinoM,etal.Antiproliferativeandcytotoxiceffectsofsomesigma2agonistsandsigma1antagonistsintumourcelllines.NaunynSchmiedebergsArchPharmacol.2004Aug;370(2):106-13.PMID:15322732.

SeemanP,TallericoT.AntipsychoticdrugswhichelicitlittleornoparkinsonismbindmorelooselythandopaminetobrainD2receptors,yetoccupyhighlevelsofthesereceptors.MolPsychiatry.1998Mar;3(2):123-34.PMID:9577836.

SchotteA,JanssenPF,MegensAA,etal.Occupancyofcentralneurotransmitterreceptorsbyrisperidone,clozapineandhaloperidol,measuredexvivobyquantitativeautorADIography.BrainRes.1993Dec24;631(2):191-202.PMID:7510574.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂