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当前位置: 首页 > 产品中心 > clinical_research > LKT/HYDROXYZINE DIHYDROCHLORIDE/H9717/5 g
商品详细LKT/HYDROXYZINE DIHYDROCHLORIDE/H9717/5 g
LKT/HYDROXYZINE DIHYDROCHLORIDE/H9717/5 g
LKT/HYDROXYZINE DIHYDROCHLORIDE/H9717/5 g
商品编号: H9717-5g
品牌: lktlabs
市场价: ¥1280.00
美元价: 768.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

HydroxyzineisafirstgenerationantihistaminethatactsasaninverseagoNISTathistamineH1receptors.Hydroxyzineexhibitsanti-allergic,antipsychotic,anxiolytic,andsedativeactivities;itistheparentcompoundofcetirizine.Hydroxyzinealsoinhibits5-HT2A,D1/2,andα1-adrenergicreceptorsandactsasafunctionalinhibitorofacidsphingomyelinase(FIASMA).

ProductInfo

CasNo.

2192-20-3

Purity

≥98%

Formula

C21H27ClN2O2•2HCl

FormulaWt.

447.83

ChemicalName

Ethanol,2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-,dihydrochloride

IUPACName

2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride

Synonym

Alamon;Atarax;Aterax;Durrax;Orgatrax;Quiess;VistarilParental.

MeltingPoint

193°C

Solubility

Solubleinwater(<700mg l),="" ethanol="" (220="" mg/ml),="" chloroform="" (60mg/ml)="" or="" acetone="">

Appearance

Whiteofalmostwhitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

H9717MSDSPDF

InfoSheet

H9717InfoSheetPDF

References

LlorcaPM,SpadoneC,SolO,etal.Efficacyandsafetyofhydroxyzineinthetreatmentofgeneralizedanxietydisorder:a3-monthdouble-blindstudy.JClinPsychiatry.2002Nov;63(11):1020-7.PMID:12444816.

MinogiannisP,El-MansouryM,BetancesJA,etal.Hydroxyzineinhibitsneurogenicbladdermastcellactivation.IntJImmunopharmacol.1998Oct;20(10):553-63.PMID:9839659.

HaraguchiK,ItoK,KotakiH,etal.Predictionofdrug-inducedcatalepsybasedondopamineD1,D2,andmuscarinicacetylcholinereceptoroccupancies.DrugMetabDispos.1997Jun;25(6):675-84.PMID:9193868.

SnowmanAM,SnyderSH.Cetirizine:actionsonneurotransmitterreceptors.JAllergyClinImmunol.1990Dec;86(6Pt2):1025-8.PMID:1979798.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂