Indomethacinisanon-steroidalanti-inflammatorydrug(NSAID)thatexhibitsanti-inflammatory,analgesic,antipyretic,tocolytic,andanti-metastaticactivities.Indomethacinisanon-selectiveCOX-1andCOX-2inhibitorthatisclinicallyusedtotreatheadaches;likeotherNSAIDs,indomethacinmayinduceintestinaldamageorgastriclesions.Indomethacindelaysprematurelaborinclinicalsettingsbydecreasinguterinecontractility.Invitro,indomethacindecreasescancercellmigrationbysuppressingCa2+influx.
| CasNo. | 53-86-1 |
|---|---|
| Purity | ≥98% |
| Formula | C19H16ClNO4 |
| FormulaWt. | 357.79 |
| ChemicalName | 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-aceticacid |
| IUPACName | 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]aceticacid |
| Synonym | Amuno;Idomethine. |
| MeltingPoint | 158-162°C |
| Solubility | Insolubleinwater.Solubleinethanol(20mg/mL),oracetone. |
| Appearance | White/YellowCrystallinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | I5315MSDSPDF |
|---|---|
| InfoSheet | I5315InfoSheetPDF |
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