MemantineisaninhibitorofNMDAreceptorsthatexhibitsneuroprotectiveandcognitionenhancingactivitiesandisclinicallyusedtotreatAlzheimer’sdisease,dementia,andParkinson’sdisease.Memantinealsoinhibits5-HT3receptorsandα7nicotinicacetylcholinereceptors(nAChRs)andactivatesD2receptors.Memantineimprovesspatiallearningandmemoryimpairmentsinvariousanimalmodelsandclinicalsettings.Additionally,memantinestimulatesdendriticspinematurationandsynapseformationinvivo.
| CasNo. | 41100-52-1 |
|---|---|
| Purity | ≥97% |
| Formula | C12H21N•HCl |
| FormulaWt. | 215.77 |
| ChemicalName | 3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-aminehydrochloride |
| IUPACName | 3,5-dimethyladamantan-1-amine;hydrochloride |
| Synonym | Akatinol |
| MeltingPoint | 258°C |
| Solubility | Solubleinwater. |
| Appearance | Whiteoroff-whitecrystalsorcrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | M1749MSDSPDF |
|---|---|
| InfoSheet | M1749InfoSheetPDF |
| Brochure | MemantineFlyer |
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