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当前位置: 首页 > 产品中心 > clinical_research > LKT/MIFEPRISTONE/M3321/100 mg
商品详细LKT/MIFEPRISTONE/M3321/100 mg
LKT/MIFEPRISTONE/M3321/100 mg
LKT/MIFEPRISTONE/M3321/100 mg
商品编号: M3321-100mg
品牌: lktlabs
市场价: ¥544.00
美元价: 326.40
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Mifepristoneisasyntheticsteroidthatexhibitsabortifacient,contraceptive,neuroprotective,cognitionenhancing,andantidepressantactivities.Mifepristoneinhibitstheglucocorticoidreceptorandprogesteronereceptor;itpreventsovulationandinducesendometrialdecidualdegeneration.Invitro,mifepristoneprotectshippocampalculturesagainstoxidativestressandcelldeathinducedbyamyloid-β(Aβ),glutamate,andH2O2,suggestingpotentialbenefitinthetreatmentofAlzheimer’sdisease.Mifepristonealsoimprovescognitivefunction,workingmemory,andspatialmemoryandimprovesymptomsofdepressioninclinicalsettings.

ProductInfo

CasNo.

84371-65-3

Purity

≥98%

Formula

C29H35NO2

FormulaWt.

429.59

ChemicalName

(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one

IUPACName

(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one

Synonym

RU-486;Mifegyne;Mifeprex

MeltingPoint

150°C

Solubility

Solubleinmethanol,chloroform,oracetone.

Appearance

YellowCrystalPowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

MSDS

M3321MSDSPDF

InfoSheet

M3321InfoSheetPDF

References

FialaC,Gemzel-DanielssonK.Reviewofmedicalabortionusingmifepristoneincombinationwithaprostaglandinanalogue.Contraception.2006Jul;74(1):66-86.PMID:16781264.

YoungAH,GallagherP,WatsonS,etal.Improvementsinneurocognitivefunctionandmoodfollowingadjunctivetreatmentwithmifepristone(RU-486)inbipolardisorder.Neuropsychopharmacology.2004Aug;29(8):1538-45.PMID:15127079.

BehlC,TrappT,SkutellaT,etal.Protectionagainstoxidativestress-inducedneuronalcelldeath--anovelroleforRU486.EurJNeurosci.1997May;9(5):912-20.PMID:9182944.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂