L-5-hydroxytryptophan(L-5-HTP)isanendogenousaminoacidprecursorof5-HTandmelatoninthatiscommonlyfoundindietarysupplements.L-5-HTPexhibitsantidepressantandantioxidativeactivities.L-5-HTPactsasanantidepressantinclinicalsettingsandshiftscircADIanrhythmsinanimalmodels.ThiscompoundalsoinhibitsUV-inducedapoptosisinmonocytes.
| CasNo. | 4350-09-8 |
|---|---|
| Purity | ≥98% |
| Formula | C11H12N2O3 |
| FormulaWt. | 220.22 |
| IUPACName | (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacid |
| Synonym | L-5HTP;Oxitriptan;Cincofarm;Levothym;Oxyfann;Telestol |
| MeltingPoint | 270°C(dec) |
| Solubility | Slightlysolubleinwater. |
| Appearance | WhitetoGrayFInePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | H9714InfoSheetPDF |
|---|
JangidP,MalikP,SinghP,etal.Comparativestudyofefficacyofl-5-hydroxytryptophanandfluoxetineinpatientspresentingwithfirstdepressiveepisode.AsianJPsychiatr.2013Feb;6(1):29-34.PMID:23380314.
BasuP,SingaravelM,HaldarC.L-5-hydroxytryptophanresetsthecircadianlocomotoractivityrhythmofthenocturnalIndianpygmyfieldmouse,Musterricolor.Naturwissenschaften.2012Mar;99(3):233-9.PMID:22331255.
LysekN,KinscherfR,ClausR,etal.L-5-Hydroxytryptophan:antioxidantandanti-apoptoticprincipleoftheintertidalspongeHymeniacidonheliophila.ZNaturforschC.2003Jul-Aug;58(7-8):568-72.PMID:12939046.
