Description
Lavendustin A inhibits various tyrosine kinases and exhibits neuroprotective activity, increasing axonal outgrowth in neurons; this compound is used in research models to examine the effects of tyrosine kinases.
Lavendustin A inhibits various tyrosine kinases and exhibits neuroprotective activity, increasing axonal outgrowth in neurons; this compound is used in research models to examine the effects of tyrosine kinases.
Cas No. | 125697-92-9 |
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Purity | ≥97% |
Formula | C21H19NO6 |
Formula Wt. | 381.38 |
Chemical Name | 5-Amino-[(N-2,5-dihydroxybenzyl)-N'-2-hydroxy- benzyl]salicylic Acid |
IUPAC Name | 5-[(2,5-dihydroxyphenyl)methyl-[(2-hydroxyphenyl)methyl]amino]-2-hydroxybenzoic acid |
Synonym | 5-[[(2,5-Dihydroxyphenyl)methyl][(2-hydroxyphenyl)- methyl]amino]-2-hydroxybenzoic acid |
Melting Point | 158°C |
Solubility | Soluble in DMSO or ethanol, or acetic acid. |
Appearance | White to off-white crystal |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet | L0284 Info Sheet PDF |
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Rojas A, Wetherington J, Shaw R, et al. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol. 2013 Jan;83(1):106-21. PMID: 23066089.
Kim HJ, Ahn HS, Choi BH, et al. Inhibition of Kv4.3 by genistein via a tyrosine phosphorylation-independent mechanism. Am J Physiol Cell Physiol. 2011 Mar;300(3):C567-75. PMID: 21148405.
Murakami K, Kanno H, Yamamoto I, et al. Lavendustin A enhances axon elongation in VHL gene-transfected neural stem cells. Neuroreport. 2004 Mar 22;15(4):611-4. PMID: 15094462.