LKT/LEVETIRACETAM/L1784/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/LEVETIRACETAM/L1784/100 mg

LKT/LEVETIRACETAM/L1784/100 mg

商品编号： L1784-100mg

品牌： lktlabs

市场价： ¥1440.00

美元价： 864.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDL1784

CasNo.102767-28-2

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Levetiracetamisclinicallyusedtotreatawidevarietyofseizuredisorders,includingpartial,myoclonic,andtonic-clonicseizuresaswellasmoodandpsychiatricdisorderssuchasanxiety,autism,andTourette’ssyndrome.Levetiracetamdisplaysanticonvulsant/antiepileptic,neuromodulatory,anxiolytic,andcognitionenhancingactivities.LevetiracetambindstosynapticvesicleglycoproteinSV2A,amembraneglycoproteincommontoallsynapticandendocrinevesicles.SV2AplaysaroleinCa2+-inducedvesiclefusion,actionpotentialproliferation,normalCNSfunction,andsurvival.AlteringSV2AfunctioninhibitspresynapticCa2+release,reducesexcitatorypostsynapticpotentials,andinhibitssynaptictransmission.ThiscompoundisalsounderexaminationasapotentialtreatmentforAlzheimer’sdisease,asitreducesmemoryandlearningdeficits,synapticdysfunction,andhippocampalremodelinginatransgenicmurinemodelofthedisease.

ProductInfo

CasNo.	102767-28-2
Purity	≥98%
Formula	C₈H₁₄N₂O₂
FormulaWt.	170.21
ChemicalName	2(S)-(2-oxopyrrolidin-1-yl)butyramide
IUPACName	(2S)-2-(2-oxopyrrolidin-1-yl)butanamide
MeltingPoint	117°C
Solubility	SolubleinDMSO,water,andethanol,allto34mg/mL
Appearance	Whitetooffwhitepowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	L1784MSDSPDF
InfoSheet	L1784InfoSheetPDF

References

VoglC,MochidaS,WolffC,etal.Thesynapticvesicleglycoprotein2AligandlevetiracetaminhibitspresynapticCa2+channelsthroughanintracellularpathway.MolPharmacol.2012Aug;82(2):199-208.PMID:22554805.

SanchezPE,ZhuL,VerretL,etal.LevetiracetamsuppressesneuronalnetworkdysfunctionandreversessynapticandcognitivedeficitsinanAlzheimer"sdiseasemodel.ProcNatlAcadSciUSA.2012Oct16;109(42):E2895-903.PMID:22869752.

FarooqMU,BhattA,MajidA,etal.Levetiracetamformanagingneurologicandpsychiatricdisorders.AmJHealthSystPharm.2009Mar15;66(6):541-61.PMID:19265183.

LynchBA,LambengN,NockaK,etal.ThesynapticvesicleproteinSV2Aisthebindingsitefortheantiepilepticdruglevetiracetam.ProcNatlAcadSciUSA.2004Jun29;101(26):9861-6.PMID:15210974.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂