N-(4-Carbethoxyphenyl)retinamideisaretinoidthatexhibitsanticancerchemotherapeuticandchemopreventiveactivities.Thiscompoundinhibitsdevelopmentofstomachandoralcancersinvivoandshowssomebenefitinthetreatmentofdysplasias.Additionally,thiscompoundinducesdifferentiationinleukemiacells.
| CasNo. | 53839-71-7 |
|---|---|
| Purity | ≥98% |
| Formula | C29H37NO3 |
| FormulaWt. | 447.62 |
| IUPACName | ethyl4-[[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoyl]amino]benzoate |
| Synonym | 4-(Ethoxycarbophenyl)retinamide;N-(Carbo-ethoxyphenyl)retinamide |
| MeltingPoint | 174-179°C |
| Solubility | SolubleinDMSOorethanol. |
| Appearance | YellowPowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | C0170InfoSheetPDF |
|---|
HanJ.HighlightsofthecancerchemopreventionstudiesinChina.PrevMed.1993Sep;22(5):712-22.PMID:8234211.
SongZP,LiuYH,HanR.Differentiationofhumanpromyelocyticleukemia(HL-60)cellsinducedbynewsyntheticretinoids4-(ethoxycarbophenyl)retinamideand4-(hydroxycarbophenyl)retinamide.YaoXueXueBao.1984Aug;19(8):576-81.PMID:6399190.
