n-Octylcaffeateexhibitsantioxidative,anti-metastatic,anticancerchemotherapeutic,andchemopreventiveactivities.n-Octylcaffeatedecreaseslipidperoxidation,activityofxanthineoxidase,activationofJNKandERK,andproductionofNOandiNOSinratbrainhomogenate;italsopreventstheLPS-induceddropinmeanarterialpressureinaorticsmoothmusclecells.Inanimalmodelsoftumormetastasis,n-octylcaffeatedecreasestumornodules.
| CasNo. | 478392-41-5 |
|---|---|
| Purity | ≥98% |
| Formula | C17H24O4 |
| FormulaWt. | 292.37 |
| IUPACName | Octyl(2E)-3-(3,4-dihydroxyphenyl)acrylate |
| Synonym | Caffeicacidn-octylester,3,4-dihydroxycinnamicacidn-octylester. |
| Appearance | WhitePowder |
| StoreTemp | 4°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | O1176MSDSPDF |
|---|---|
| InfoSheet | O1176InfoSheetPDF |
NagaokaT,BanskotaAH,TezukaY,etal.Inhibitoryeffectsofcaffeicacidphenethylesteranaloguesonexperimentallungmetastasisofmurinecolon26-L5carcinomacells.BiolPharmBull.2003May;26(5):638-41.PMID:12736504.
HsiaoG,ShenMY,ChangWC,etal.Anovelantioxidant,octylcaffeate,suppressionofLPS/IFN-gamma-inducedinducIBLenitricoxidesynthasegeneexpressioninrataorticsmoothmusclecells.BiochemPharmacol.2003Apr15;65(8):1383-92.PMID:12694879.
