Gestrinoneisasyntheticanti-progestinhormonethatactsasanantagoNISTatestrogenandprogesteronereceptorsandasanagonistatandrogenreceptors.Gestrinoneisprimarilyusedtotreatendometriosisinclinicalsettings;itisalsoinclinicaltrialsforpotentialuseasanemergencycontraceptive.Thiscompoundalsoexhibitssomepotentialanticanceractivityaswell,downregulatingexpressionoftheprogesteronereceptor,estrogenreceptor,andp-Src,inhibitinggrowthofuterineleiomyomacells.
| CasNo. | 16320-04-0 |
|---|---|
| Purity | ≥98% |
| Formula | C21H24O2 |
| FormulaWt. | 308.41 |
| ChemicalName | (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,9,11-trien-20-yn-3-one |
| IUPACName | (8S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
| Synonym | 13b-ethyl-17a-ethynyl-17b-hydroxy-4,9,11-gonatrien-3-one;13b-ethyl-17a-ethynyl-D4,9,11-gonatriene-17b-ol-3-one;ethylnorgestrienone |
| MeltingPoint | 154°C |
| Appearance | Yellowishcrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | G1975MSDSPDF |
|---|---|
| InfoSheet | G1975InfoSheetPDF |
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