Mitoxantroneisananthracenedionethatexhibitsimmunosuppressiveandanticancerchemotherapeuticactivities.Mitoxantroneisclinicallyusedtotreatmultiplesclerosis(MS),breastcancer,non-Hodgkin’slymphoma,acutemyeloidleukemia(AML),andacutelymphoblasticleukemia(ALL).Mitoxantroneactsasanintercalator,cross-linkingandformingcomplexesinDNA,inhibitingDNAsynthesis;italsoinhibitsPim-1kinase.
| CasNo. | 70476-82-3 |
|---|---|
| Purity | ≥98% |
| Formula | C22H28N4O6•2HCl |
| FormulaWt. | 517.41 |
| ChemicalName | 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]-ethyl]amino]-9,10-anthracenedionedihydrochloride |
| IUPACName | 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride |
| Synonym | Mitoxantronehydrochloride;Novantrone |
| MeltingPoint | 160-162°C |
| Solubility | Solubleinwater. |
| Appearance | Blue/BlackCrystallinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | M3379MSDSPDF |
|---|---|
| InfoSheet | M3379InfoSheetPDF |
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