LKT/LORATADINE/L5767/500 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/LORATADINE/L5767/500 mg

LKT/LORATADINE/L5767/500 mg

商品编号： L5767-500mg

品牌： lktlabs

市场价： ¥1260.00

美元价： 756.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Product ID L5767

Cas No. 79794-75-5

Purity ≥98%

Description
Product Info
Shipping and Storage
Downloads
References

Description

Loratadine is a non-sedating antihistaminergic that acts as an antagonist at histamine H1 receptors that exhibits anti-inflammatory, anti-allergic, anti-asthma, and anticancer chemotherapeutic activities. Loratadine is clinically used to treat allergic rhinitis, chronic idiopathic urticaria, and asthma. In vivo, loratadine inhibits growth of colon cancer xenografts through decreases expression of cyclin B1 and Chk1, the induction of G2/M phase cell cycle arrest, and direct damage to DNA. Loratadine also acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

Product Info

Cas No.	79794-75-5
Purity	≥98%
Formula	C₂₂H₂₃ClN₂O₂
Formula Wt.	382.88
Chemical Name	4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta- [1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
IUPAC Name	ethyl4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
Synonym	Claritin; Lisino
Melting Point	134-136°C
Solubility	Soluble in DMSO (26mg/mL). Insoluble in water.
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	L5767 MSDS PDF
Info Sheet	L5767 Info Sheet PDF

References

Soule BP, Simone NL, DeGraff WG, et al. Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines. Radiat Oncol. 2010 Feb 3;5:8. PMID: 20128919.

DuBuske LM. Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders. Expert Opin Pharmacother. 2005 Nov;6(14):2511-23. PMID: 16259582.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂