Description
Lomustineisanitrosoureaalkylatorthatexhibitsanticancerchemotherapeuticactivity.Lomustineisclinicallyusedtotreatvariousformsofcancerandisonecomponentofthe“PCV”regimen.
Lomustineisanitrosoureaalkylatorthatexhibitsanticancerchemotherapeuticactivity.Lomustineisclinicallyusedtotreatvariousformsofcancerandisonecomponentofthe“PCV”regimen.
CasNo. | 13010-47-4 |
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Purity | ≥98% |
Formula | C9H16ClN3O2 |
FormulaWt. | 233.70 |
ChemicalName | N-(2-Chloroethyl)-N"-cyclohexyl-N-nitrosourea |
IUPACName | 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea |
Synonym | Belustine;Cecenu"CeeNU;CiNU |
MeltingPoint | 90°C |
Solubility | Solubleinethanolorchloroformoracetone. |
Appearance | YellowishCrystal |
StoreTemp | 4°C |
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ShipTemp | Ambient |
MSDS | L5648MSDSPDF |
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InfoSheet | L5648InfoSheetPDF |
BuccheriG,FerrignoD,RossoA.AphaseIIstudyofmethotrexate,doxorubicin,cyclophosphamide,andlomustinechemotherapyandlonidamineinadvancednon-smallcelllungcancer.Cancer.1993Sep1;72(5):1564-72.PMID:8394198.
KamiyaS.Synthesisofantitumornitrosoureaderivativesandchemicalstudiesoftheirmechanismofaction.EiseiShikenjoHokoku.1986;(104):1-19.PMID:3471287.