Hydrocortisoneisasteroidhormonethatisproducedintheadrenalcortexandisinvolvedinstresssignaling.Hydrocortisoneisaglucocorticoidandisalsoknownascortisolinitsendogenousform;itexhibitsanti-inflammatoryandimmunomodulatoryactivities.Hydrocortisoneisclinicallyusedtotreateczema,psoriasis,gout,andsevereallergicreactions.Hydrocortisonestimulatesgluconeogenesis,inhibitsinflammatorycytokineproduction,andshiftstheimmuneresponsefromTh1toTh4subtype.
| CasNo. | 50-03-3 |
|---|---|
| Purity | ≥98% |
| Formula | C23H32O6 |
| FormulaWt. | 404.50 |
| ChemicalName | (11β)11,17,21-Trihydroxypregn-4-ene-3,20-dione21-acetate |
| IUPACName | [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl]acetate |
| Synonym | Colifoam;Cortaid;Cortifoam;Hydrocal;Lanacort;Sigmacort;Velopural |
| MeltingPoint | 223°C(dec) |
| Solubility | SolubleinDMFanddioxane.Slightlysolubleinchloroform,ethanol(4mg/mL),methanol.etherandwater. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | H9612MSDSPDF |
|---|---|
| InfoSheet | H9612InfoSheetPDF |
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