LKT/IRSOGLADINE MALEATE/I7074/500 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/IRSOGLADINE MALEATE/I7074/500 mg

LKT/IRSOGLADINE MALEATE/I7074/500 mg

商品编号： I7074-500mg

品牌： lktlabs

市场价： ¥6360.00

美元价： 3816.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDI7074

CasNo.84504-69-8

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

IrsoglADIneexhibitsanti-inflammatory,anti-fibrotic,andmucoprotectiveactivities.Irsogladinedecreasesnon-steroidalanti-inflammatorydrug(NSAID)-inducedintestinalmucosalinjury,ulcers,andesophagitis;itinhibitsCOX-1andCOX-2.Inanimalmodelsofcolitis,irsogladinepreventsDDS-inducedincreasesinTGF-β1,collagentype1,MMP2,TIMP-1,andα-SMA,preventingfibrosis.Additionally,irsogladinenon-selectivelyinhibitsphosphodiesterases,increasingcAMPandNO,facilitatinggapjunctioncommunicationandalteringgastricmucosalbloodflow.

ProductInfo

CasNo.	84504-69-8
Purity	≥98%
Formula	C₉H₇Cl₂N₅•C₄H₄O₄
FormulaWt.	372.17
ChemicalName	6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diaminemaleate
IUPACName	(Z)-but-2-enedioicacid;6-(2,5-dichlorophenyl)-1,3,5-triazine-2,4-diamine
Synonym	MN-1695;Gaslon
MeltingPoint	289-294°C
Solubility	SolubleinDMSO.
Appearance	WhiteCrystallinePowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	I7074InfoSheetPDF

References

KuramotoT,UmegakiE,NoudaS,etal.Preventiveeffectofirsogladineoromeprazoleonnon-steroidalanti-inflammatorydrug-inducedesophagitis,pepticulcers,andsmallintestinallesionsinhumans,aProspectiverandomizedcontrolledstudy.BMCGastroenterol.2013May14;13:85.PMID:23672202.

AkagiM,AmagaseK,MurakamiT,etal.Irsogladine:overviewofthemechanismsofmucosalprotectiveandhealing-promotingactionsinthegastrointestinaltract.CurrPharmDes.2013;19(1):106-14.PMID:22950502.

YamaguchiH,SuzukiK,NagataM,etal.Irsogladinemaleateamelioratesinflammationandfibrosisinmicewithchroniccolitisinducedbydextransulfatesodium.MedMolMorphol.2012Jun;45(3):140-51.PMID:23001296.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂