GSK-1838705Aisaninhibitorofanaplasticlymphomakinase(ALK)andIGF-1Rthatexhibitsanticancerchemotherapeuticactivity.Thiscompoundinhibitscellandtumorgrowthinavarietyofcancers,includingnon-smallcelllungcancer(NSCLC),neuroblastoma,andlarge-celllymphoma.
| CasNo. | 1116235-49-7 |
|---|---|
| Purity | ≥98% |
| Formula | C27H29FN8O3 |
| FormulaWt. | 532.57 |
| Synonym | GSK1838705A |
| Appearance | Yellowtopaleyellowpowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | G7540InfoSheetPDF |
|---|
SabbatiniP,KorenchukS,RowandJL,etal.GSK1838705Ainhibitstheinsulin-likegrowthfactor-1receptorandanaplasticlymphomakinaseandshowsantitumoractivityinexperimentalmodelsofhumancancers.MolCancerTher.2009Oct;8(10):2811-20.PMID:19825801.
