Description
Kobe2602isaninhibitorofRasthatexhibitsanticancerchemotherapeuticactivities.Invitro,thiscompoundinhibitscellgrowthandinducesapoptosisandinvivo,itdecreasestumorgrowth.
Kobe2602isaninhibitorofRasthatexhibitsanticancerchemotherapeuticactivities.Invitro,thiscompoundinhibitscellgrowthandinducesapoptosisandinvivo,itdecreasestumorgrowth.
CasNo. | 454453-49-7 |
---|---|
Purity | ≥98% |
Formula | C14H9F4N5O4S |
FormulaWt. | 419.31 |
IUPACName | 2-[2,6-Dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)hydrazinecarbothioamide |
StoreTemp | -20°C |
---|---|
ShipTemp | Ambient |
InfoSheet | K5606InfoSheetPDF |
---|
ShimaF,YoshikawaY,YeM,etal.Insilicodiscoveryofsmall-moleculeRasinhibitorsthatdisplayantitumoractivitybyblockingtheRas-effectorinteraction.ProcNatlAcadSciUSA.2013May14;110(20):8182-7.PMID:23630290.
ShimaF,YoshikawaY,MatsumotoS,etal.Discoveryofsmall-moleculeRasinhibitorsthatdisplayantitumoractivitybyinterferingwithRas·GTP-effectorinteraction.Enzymes.2013;34Pt.B:1-23.PMID:25034098.