Description
Ifosfamideisanitrogenmustardalkylatorthatexhibitsanticancerchemotherapeuticactivity.Ifosfamideisclinicallyusedtotreatvariouscancers.Becauseifosfamideisverycytotoxic,itisoftenco-admiNISTeredwithcytoprotectiveagentssuchasMESNA.
Ifosfamideisanitrogenmustardalkylatorthatexhibitsanticancerchemotherapeuticactivity.Ifosfamideisclinicallyusedtotreatvariouscancers.Becauseifosfamideisverycytotoxic,itisoftenco-admiNISTeredwithcytoprotectiveagentssuchasMESNA.
CasNo. | 3778-73-2 |
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Purity | ≥98% |
Formula | C7H15Cl2N2O2P |
FormulaWt. | 261.09 |
ChemicalName | N,3-Bis(2-chloroethyl)-tetrahydro-2H-1,3,2-oxaza-phosphorin-2-amine2-oxide |
IUPACName | N,3-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine |
Synonym | Holoxan;Ifex;Ifomide;Isoendoxan;Isophosphamide;Mitoxana |
MeltingPoint | 39-41°C,51.0°C |
Solubility | Solubleinwater. |
Appearance | WhiteCrystalPowder |
StoreTemp | Ambient |
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ShipTemp | Ambient |
MSDS | I2056MSDSPDF |
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InfoSheet | I2056InfoSheetPDF |
VincenziB,FrezzaAM,SantiniD,etal.Newtherapiesinsofttissuesarcoma.ExpertOpinEmergDrugs.2010Jun;15(2):237-48.PMID:20465449.
NissimI,HorynO,DaikhinY,etal.Ifosfamide-inducednephrotoxicity:mechanismandprevention.CancerRes.2006Aug1;66(15):7824-31.PMID:16885387.