Description
Ifosfamideisanitrogenmustardalkylatorthatexhibitsanticancerchemotherapeuticactivity.Ifosfamideisclinicallyusedtotreatvariouscancers.Becauseifosfamideisverycytotoxic,itisoftenco-admiNISTeredwithcytoprotectiveagentssuchasMESNA.
Ifosfamideisanitrogenmustardalkylatorthatexhibitsanticancerchemotherapeuticactivity.Ifosfamideisclinicallyusedtotreatvariouscancers.Becauseifosfamideisverycytotoxic,itisoftenco-admiNISTeredwithcytoprotectiveagentssuchasMESNA.
| CasNo. | 3778-73-2 |
|---|---|
| Purity | ≥98% |
| Formula | C7H15Cl2N2O2P |
| FormulaWt. | 261.09 |
| ChemicalName | N,3-Bis(2-chloroethyl)-tetrahydro-2H-1,3,2-oxaza-phosphorin-2-amine2-oxide |
| IUPACName | N,3-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine |
| Synonym | Holoxan;Ifex;Ifomide;Isoendoxan;Isophosphamide;Mitoxana |
| MeltingPoint | 39-41°C,51.0°C |
| Solubility | Solubleinwater. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | I2056MSDSPDF |
|---|---|
| InfoSheet | I2056InfoSheetPDF |
VincenziB,FrezzaAM,SantiniD,etal.Newtherapiesinsofttissuesarcoma.ExpertOpinEmergDrugs.2010Jun;15(2):237-48.PMID:20465449.
NissimI,HorynO,DaikhinY,etal.Ifosfamide-inducednephrotoxicity:mechanismandprevention.CancerRes.2006Aug1;66(15):7824-31.PMID:16885387.