- Description
- Product Info
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- References
Description
Cytochalasin A is a mycotoxin actin polymerization inhibitor initially produced by species of Aspergillus. Cytochalasin A inhibits platelet-mediated adhesion of tumor cells to the endothelial matrix, displaying potential anticancer benefit. Cytochalasin A also inhibits Kv1.5 K+ channels in vitro. This compound’s disruption of actin polymerization also prevents phagocytosis in macrophages.
Product Info
14110-64-6 |
≥98% |
C29H35NO5 |
477.60 |
193-195°C |
White Powder |
Shipping and Storage
4°C |
Ambient |
Downloads
C9878 Info Sheet PDF |
References
Choi BH, Park JA, Kim KR, et al. Direct block of cloned hKv1.5 channel by cytochalasins, actin-disrupting agents. Am J Physiol Cell Physiol. 2005 Aug;289(2):C425-36. PMID: 15800051.
Menter DG, Sloane BF, Steinert BW, et al. Platelet enhancement of tumor cell adhesion to subendothelial matrix: role of platelet cytoskeleton and platelet membrane. J Natl Cancer Inst. 1987 Nov;79(5):1077-90. PMID: 3479634.
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